Olprinone Hydrochloride is a highly selective phosphodiesterase 3 (PDE3) inhibitor designed for advanced cardiovascular therapeutic applications. Acting as a potent cardiotonic agent, it provides critical positive inotropic and vasodilating effects, making it an essential tool for increasing cardiac output and enhancing hemodynamic stability in complex clinical settings.
Beyond its primary cardiovascular role, Olprinone Hydrochloride has demonstrated significant efficacy in improving microcirculation and attenuating systemic inflammation. Its specialized application in weaning patients from cardiopulmonary bypass (CPB) and its antioxidative properties against oxidative lung injury highlight its versatility as a high-purity pharmaceutical intermediate for critical care medicine.
Detailed Parameters
| Molecular Formula | C14H10N4O • HCl | Molecular Weight | 286.7 |
|---|---|---|---|
| Purity Level | ≥98% | CAS/Synonyms | Olprinone hydrochloride; Loprinone hydrochloride |
| Certifications | GMP certificate, CFDA | Canonical SMILES | CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl |
| Storage Condition | -20°C | Stability Period | ≥ 4 years |
| Shipping Method | Room Temperature (US Continental) | Chemical Class | PDE3 Inhibitor / Pharmaceutical Intermediate |
Key Advantages
High Purity Grade
Ensuring ≥98% purity for rigorous pharmaceutical synthesis and clinical research reliability.
Long-term Stability
Exceptional stability profile exceeding 4 years when stored under recommended conditions.
Dual Action Effect
Combines positive inotropic effects with vasodilation to optimize cardiac output efficiency.
Anti-Inflammatory
Proven capability to attenuate inflammation and improve microcirculatory flow.
Regulatory Compliant
Manufactured under strict GMP standards and CFDA certification for global quality assurance.
Specialized Utility
Ideal for CPB weaning protocols and combating meconium-induced oxidative lung injury.
Product Gallery
Management Platforms
Quality Control
Rigorous batch testing using HPLC to ensure purity and structural integrity.
Supply Chain
Optimized logistics ensuring temperature-controlled shipping and rapid delivery.
Regulatory Support
Comprehensive documentation support for CFDA and GMP compliance audits.
Formulation Aid
Expert technical support for customized formulation change requests.
Inventory Tracking
Real-time tracking of API stocks to prevent production downtime.
Safety Management
Strict adherence to MSDS protocols for safe handling of chemical intermediates.
Investment Return Comparison
| Performance Metric | Standard API Grade | Our Premium Olprinone |
|---|---|---|
| Purity Level | ≥95% | ≥98% (High Precision) |
| Shelf Life | 2-3 Years | ≥ 4 Years |
| Regulatory Approval | Basic Grade | GMP & CFDA Certified |
| Delivery Speed | Standard Lead Time | Expedited Global Shipping |
| Technical Support | Limited | Full Formulation Assistance |
Frequently Asked Questions
Olprinone Hydrochloride acts as a selective phosphodiesterase 3 (PDE3) inhibitor, which increases cardiac contractility (positive inotropic effect) and promotes vasodilation.
To ensure a stability period of 4 years or more, it must be stored at -20°C in a dry, protected environment.
Yes, we accept formulation change requests to meet specific pharmaceutical requirements for different drug delivery systems.
Our products are supplied with comprehensive GMP certificates and CFDA documentation to ensure international quality standards.
Yes, Olprinone has shown potent antioxidative and anti-inflammatory effects, particularly in studies involving meconium-induced oxidative lung injury.
While stored at -20°C, it is shipped at room temperature within the continental US; however, shipping protocols may vary for other regions to ensure stability.
Ready to Integrate High-Purity Olprinone into Your Pipeline?
Contact UsRead Our Latest News
Jun.09，2026
High Quality API Products Pharma for Modern Medicine Safety
Understanding the Role of API Products Pharma in Modern Medicine In the complex world of drug development, the foundation of every medication lies in its Active Pharmaceutical Ingredient API. The demand for high-quality api products pharma is critical for ensuring the efficacy, safety, and stability of the final pharmaceutical dosage form. Whether it is a simple analgesic or a complex biologic, the API is the component directly responsible for the therapeutic effect on the patient. For pharmaceutical manufacturers, sourcing these components from reputable suppliers is not just a matter of business, but a matter of public health and regulatory compliance.
Read More
Apr.16，2026
Strategic Growth and Quality Guide for api pharma business
The global pharmaceutical landscape is evolving rapidly, placing a heightened emphasis on the quality and reliability of Active Pharmaceutical Ingredients (APIs). Navigating the api pharma business requires a deep understanding of regulatory compliance, chemical synthesis innovation, and supply chain resilience. For companies aiming to scale, the ability to source high-purity intermediates and maintain stringent quality control is the cornerstone of success. In this guide, we will explore the critical components of managing a successful API enterprise, from regulatory hurdles to the integration of green chemistry, ensuring your business remains competitive in an increasingly demanding market.
Read More
Apr.09，2026
Importance and Quality Standards of api of pharmaceutical
In the complex world of drug manufacturing, the api of pharmaceutical, or Active Pharmaceutical Ingredient, serves as the biological heart of any medication. While a pill may contain various fillers, binders, and coatings, the API is the specific component responsible for producing the desired therapeutic effect in the patient. Ensuring the purity, stability, and efficacy of these ingredients is not just a technical requirement but a critical safety mandate for global healthcare. From simple pain relievers to complex oncology treatments, the quality of the API dictates the success of the final medical product.
Read More