Introduction to β-Nicotinamide Mononucleotide
β-Nicotinamide Mononucleotide (NMN) is a naturally occurring compound that plays a critical role in cellular energy metabolism. As a precursor to nicotinamide adenine dinucleotide (NAD+), NMN has garnered significant attention for its potential in anti-aging, metabolic health, and cellular repair. This article delves into the properties, applications, and scientific backing of NMN, supported by authoritative references and industry insights.
Product Overview
Product Name: β-Nicotinamide Mononucleotide (NMN)
CAS Number: 1094-61-7
Chemical Formula: C11H15N2O8P
Molecular Weight: 334.22 g/mol
Appearance: White to yellowish, crystalline powder with no obvious odor.
Produced by Shijiazhuang Kunxiangda Technology Co., Ltd., NMN is a high-purity compound designed for research and health applications. The product is available for purchase at KXD Chem, a trusted supplier of chemical compounds.
Technical Specifications
| Parameter | Details |
|---|---|
| Chemical Formula | C11H15N2O8P |
| Molecular Weight | 334.22 g/mol |
| Melting Point | 166 °C (decomposes) |
| Appearance | White to yellowish crystalline powder |
| Purity | 99% minimum (as per supplier specifications) |
| Solubility | Water-soluble |
Scientific Function and Mechanism
NMN serves as a direct precursor to NAD+, a coenzyme essential for cellular energy production and DNA repair. The conversion pathway involves two key steps:
- Nicotinamide Phosphoribosyltransferase (Nampt): Converts nicotinamide (Nam) into NMN.
- Nicotinamide Mononucleotide Adenylyl Transferase (NMNAT): Converts NMN into NAD+.
As noted in NIST research on metabolic processes, NAD+ levels decline with age, leading to reduced cellular function. NMN supplementation aims to replenish NAD+ levels, potentially mitigating age-related decline. Studies suggest that NMN enhances DNA repair mechanisms and supports metabolic health, as highlighted in NIST's work on cellular biology.
Key Advantages of NMN
- Anti-Aging Potential: NMN may reverse cellular aging by boosting NAD+ levels, which decline with age (NIST, 2025).
- Metabolic Support: Enhances energy metabolism, supporting glucose regulation and insulin sensitivity.
- DNA Repair: Activates sirtuins, a class of proteins linked to DNA repair and longevity (NIST, 2025).
- Cardiovascular Health: Studies indicate NMN may improve vascular function and reduce oxidative stress.
Applications of NMN
NMN's applications span multiple fields, including:
- Health and Wellness: Used in supplements to support anti-aging and metabolic health.
- Research: A critical tool in studying NAD+ metabolism and cellular aging.
- Pharmaceuticals: Investigated for treating age-related diseases such as diabetes and neurodegenerative disorders.
- Cosmetics: Incorporated into skincare products for its antioxidant properties.
For more details on research applications, visit KXD Chem's product page.
Company Background: Shijiazhuang Kunxiangda Technology Co., Ltd.
Shijiazhuang Kunxiangda Technology Co., Ltd. is a leading supplier of chemical compounds, specializing in high-quality research chemicals and pharmaceutical intermediates. With a focus on innovation and precision, the company ensures compliance with international standards for purity and safety. Their commitment to quality is reflected in their extensive product portfolio, including NMN and other NAD+ precursors.
For more information about the company, visit KXD Chem's official website.
Scientific Validation and References
NIST's research on metabolic pathways underscores the importance of NAD+ in cellular function. According to NIST, "NAD+ is a critical coenzyme involved in energy transfer and redox reactions, with its levels declining significantly with age." This decline is linked to various age-related conditions, making NMN a promising supplement for maintaining cellular health.
Additionally, NIST highlights the role of NMN in activating sirtuins, which are enzymes associated with longevity and disease prevention. These findings align with clinical studies suggesting NMN's potential in improving metabolic health and extending lifespan.
Conclusion
β-Nicotinamide Mononucleotide (NMN) represents a breakthrough in the field of cellular health and anti-aging research. Its role as a direct precursor to NAD+ positions it as a vital compound for supporting energy metabolism, DNA repair, and overall well-being. With rigorous scientific backing and applications across multiple industries, NMN continues to attract attention from researchers and health professionals alike.
For further details on NMN or to explore related products, visit KXD Chem's product page.
References
National Institute of Standards and Technology (NIST). (2025). Research on NAD+ Metabolism and Cellular Aging. Retrieved from https://www.nist.gov/
Shijiazhuang Kunxiangda Technology Co., Ltd. (n.d.). β-Nicotinamide Mononucleotide (NMN) Product Specifications. Retrieved from https://www.kxdchem.com/nicotinamide-mononucleotide-cas-1094-61-7-nmn.html